Bats are natural reservoirs of SARS-like coronaviruses.

نویسندگان

  • Wendong Li
  • Zhengli Shi
  • Meng Yu
  • Wuze Ren
  • Craig Smith
  • Jonathan H Epstein
  • Hanzhong Wang
  • Gary Crameri
  • Zhihong Hu
  • Huajun Zhang
  • Jianhong Zhang
  • Jennifer McEachern
  • Hume Field
  • Peter Daszak
  • Bryan T Eaton
  • Shuyi Zhang
  • Lin-Fa Wang
چکیده

Severe acute respiratory syndrome (SARS) emerged in 2002 to 2003 in southern China. The origin of its etiological agent, the SARS coronavirus (SARS-CoV), remains elusive. Here we report that species of bats are a natural host of coronaviruses closely related to those responsible for the SARS outbreak. These viruses, termed SARS-like coronaviruses (SL-CoVs), display greater genetic variation than SARS-CoV isolated from humans or from civets. The human and civet isolates of SARS-CoV nestle phylogenetically within the spectrum of SL-CoVs, indicating that the virus responsible for the SARS outbreak was a member of this coronavirus group.

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عنوان ژورنال:
  • Science

دوره 310 5748  شماره 

صفحات  -

تاریخ انتشار 2005